Peptide vaccine for inducing the production of anti-amyloid β-peptide antibody
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United States of America Patent
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Oct 11, 2011
Grant Date -
Mar 11, 2010
app pub date -
Feb 16, 2007
filing date -
Feb 22, 2006
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Abstract
An object of the present invention is to provide a peptide vaccine for preventing and/or treating diseases caused by amyloid β-peptide, such as Alzheimer's disease. The present invention solves the above object by providing a peptide vaccine constructed by inserting a peptide having an amino acid sequence of a cell attachment motif of a cell adhesive molecule to a peptide which consists of a peptide having an amino acid sequence of multiagretope type T-cell epitope, which has been generated immunological memory, or a peptide including the same; an linker peptide; and a peptide having an amino acid sequence of a B cell epitope which is a specific region of amyloid β-peptide or a peptide including the same.
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