Antisense modulation of PTP1B expression

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United States of America Patent

PATENT NO 8017760
APP PUB NO 20090124009A1
SERIAL NO

12046421

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Abstract

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Compounds, compositions and methods are provided for modulating the expression of PTP1B. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding PTP1B. Methods of using these compounds for modulation of PTP1B expression and for treatment of diseases associated with expression of PTP1B are provided.

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Patent Owner(s)

Patent OwnerAddress
ISIS PHARMACEUTICALS INCCARLSBAD CA 92008

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bhanot, Sanjay Carlsbad, US 116 1865
Butler, Madeline M Rancho Santa Fe, US 30 238
Cowsert, Lex M New Braunfels, US 219 3636
Dobie, Kenneth W Del Mar, US 319 3223
Freier, Susan M San Diego, US 526 6555
McKay, Robert Oceanside, US 102 2107
Monia, Brett P Encinitas, US 303 5836
Wyatt, Jacqueline R Sundance, US 43 1456

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