Detection of proteins from circulating neoplastic cells

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United States of America Patent

PATENT NO 8012480
APP PUB NO 20090098138A1
SERIAL NO

12297420

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Abstract

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The protein EGFR, ERCC1, RRM1, thymidylate synthase, or beta-tubulin from cancer cells is detected in a blood sample by enriching the cancer cells from the blood sample followed by performing on the enriched cancer cells an immunoassay capable of detecting the proteins mentioned above. Cancer patients overexpressing EGFR are treated with an anti-EGFR agent, for example cetuximab, panitumumab, erlotinib or gefitinib.

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Patent Owner(s)

Patent OwnerAddress
PHARMA CINQ LLC1601 RESEARCH BOULEVARD ROCKVILLE MD 20850

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lorence, Robert M Bethesda, US 28 296

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