Treatment of colorectal polyps with imidazoquinoline derivatives
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United States of America Patent
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Aug 30, 2011
Grant Date -
Jul 16, 2009
app pub date -
Jan 14, 2009
filing date -
Jan 15, 2008
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Abstract
The invention relates to treating colorectal polyps and precancercerous colorectal changes by topical administration of immunomodulating drugs of the imidazoquinoline family, such as imiquimod (1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine), resiquimod (4-amino-α,α-dimethyl-2-ethoxymethyl-1H-imidazo[4,5-c]quinoline-1-ethanol), sotirimod (2-methyl-1-(2-methylpropyl)-1H-imidazo[4,5-c][1,5]naphthyridin-4-amine).
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