Methods of treating cancer using immunostimulatory oligonucleotides

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United States of America Patent

PATENT NO 8008266
APP PUB NO 20040087538A1
SERIAL NO

10719493

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Abstract

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Nucleic acid sequences containing unmethylated CpG dinucleotides that modulate an immune response including stimulating a Th1 pattern of immune activation, cytokine production, NK lytic activity, and B cell proliferation are disclosed. The sequences are also useful as a synthetic adjuvant.

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Patent Owner(s)

Patent OwnerAddress
DEPARTMENT OF HEALTH AND HUMAN SERVICES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARYFDA/CBER BUILDING 29A 3D10 BETHESDA MD 20892

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Klinman, Dennis Potomac, US 68 4430
Krieg, Arthur M Wellesley, US 154 11149
Steinberg, Alfred D Potomac, US 51 3951

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