Agent derived from tortoise spleen stimulating mammalian hemopoiesis
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United States of America Patent
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Aug 23, 2011
Grant Date -
May 17, 2007
app pub date -
Aug 31, 2004
filing date -
Sep 4, 2003
priority date (Note) -
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Abstract
The present invention relates to a proteinaceous extract derived from tortoise spleen and to a tetrapeptide FTGN, which have stimulatory activity on hematopoietic cells. In particular, this tetrapeptide enhances hemopoietic reconstruction, and bone marrow re-population, reduced as a consequence of a high dose of radiation or chemotherapy exposure. The invention further provides pharmaceutical compositions comprising as an effective ingredient the proteinaceous extract or the FTGN tetrapeptide and ex vivo and in vivo methods of treatment employing them.
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