receptor antagonist peptide from amphibian skin
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United States of America Patent
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Aug 23, 2011
Grant Date -
Feb 21, 2008
app pub date -
Feb 6, 2004
filing date -
Feb 6, 2003
priority date (Note) -
Expired
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Abstract
. Also disclosed are kinestatin analogs, prodrugs including the peptides, fusion peptides and multimeric peptides including the peptide sequences, pharmaceutical compositions including kinestatin and analogs thereof, prodrugs, fusion and multimeric peptides thereof, nucleic acids encoding kinestatin and analogs thereof, and nucleic acids encoding the fusion and multimeric peptides. Kinestatin and analogs thereof (including the prodrugs and multimeric and/or fusion peptides) can be used to treat and/or prevent disorders associated with bradykinin, including cardiovascular disorders, inflammation, asthma, allergic rhinitis, pain, angiogenesis and the like.
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