Aptamers to von Willebrand factor and their use as thrombotic disease therapeutics

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United States of America Patent

PATENT NO 7998940
APP PUB NO 20090149643A1
SERIAL NO

12322078

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates generally to the field of nucleic acids and more particularly to aptamers capable of binding to von Willebrand Factor useful as therapeutics in and diagnostics of thrombotic diseases and/or other diseases or disorders in which von Willebrand Factor mediated platelet aggregation has been implicated. The invention further relates to materials and methods for the administration of aptamers capable of binding to von Willebrand Factor.

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Patent Owner(s)

Patent OwnerAddress
ARCHEMIX CORP300 THIRD STREET FIRST FLOOR CAMBRIDGE MA 02142

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Benedict, Claude Cambridge, US 14 219
Diener, John L Cambridge, US 33 577
Lagasse, H A Daniel Somerville, US 1 3

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