Aptamers that bind thrombin with high affinity

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United States of America Patent

PATENT NO 7998939
APP PUB NO 20090221680A1
SERIAL NO

11990998

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides aptamers capable of binding to thrombin useful as therapeutics for and diagnostics of coagulation related disorders and/or other diseases or disorders in which thrombin has been implicated. The invention further provides materials and methods for the administration of aptamers capable of binding to thrombin.

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Patent Owner(s)

Patent OwnerAddress
ARCHEMIX CORPORATIONONE HAMPSHIRE STREET CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Diener, John L Cambridge, US 33 577
Fontana, David Clyde Hill, US 4 20
Wagner-Whyte, Jess Lynn, US 5 195

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