Cytokine design
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United States of America Patent
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Aug 9, 2011
Grant Date -
Feb 21, 2008
app pub date -
Dec 6, 2004
filing date -
Dec 5, 2003
priority date (Note) -
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Abstract
The present invention relates to novel methods for the design of proteins, in particular, cytokines. These methods allow the stabilisation of such cytokines, as well as modification of their selectivity/specificity for their cognate receptors. The invention also relates to various modified proteins that have been designed by the methods of the invention.
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