Pharmaceutical compositions containing camptothecins
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United States of America Patent
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Aug 9, 2011
Grant Date -
Oct 19, 2006
app pub date -
Apr 18, 2005
filing date -
Apr 18, 2005
priority date (Note) -
Expired
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Abstract
A camptothecin-containing pharmaceutical composition which contains: (a) camptothecin or a derivative thereof, and (b) one or more compounds selected from among ascorbic acid or a salt thereof, sodium hydrogen sulfite, sodium sulfite, potassium pyrosulfite, sodium erythorbate, sodium thioglycolate, sodium pyrosulfite, and α-thioglycerin. The pharmaceutical composition is useful in that, after storage for a long period of time or under light-irradiation conditions, camptothecin or a derivative thereof contained therein undergoes minimum degradation.
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