Compositions and methods for determining the susceptibility of a pathogenic virus to protease inhibitors

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7993824
APP PUB NO 20040248084A1
SERIAL NO

10612603

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides an approach for developing an algorithm for determining the effectiveness of anti-viral drugs based on a comprehensive analysis of paired phenotypic and genotypic data guided by phenotypic clinical cut-offs. In one aspect, the algorithm allows one to provide a patient with effective treatment. It helps predict whether an infected individual will respond to treatment with an anti-viral compound, thereby allowing an effective treatment regimen to be designed without subjecting the patient to unnecessary side effects. Also, by avoiding the administration of ineffective drugs, considerable time and money is saved.

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Patent Owner(s)

Patent OwnerAddress
PFIZER INC66 HUDSON BOULEVARD EAST NEW YORK NY 10001

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chappey, Colombe San Francisco, US 10 40
Parkin, Neil T Belmont, US 41 333
Petropoulos, Christos J Half Moon Bay, US 29 199

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