Crystalline forms of solvated ilaprazole
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United States of America Patent
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Aug 2, 2011
Grant Date -
Aug 21, 2008
app pub date -
Dec 28, 2007
filing date -
Dec 29, 2006
priority date (Note) -
Expired
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Abstract
The invention relates to crystalline forms of various solvates of ilaprazole, 2[[(4-methoxy-3-methyl-2-pyridinyl)-methyl]sulfinyl]-5-(1H-pyrrol-1-yl)1H-Benzimidazole. The invention also relates to a pharmaceutical composition for inhibiting gastric acid secretion comprising crystalline ilaprazole hydrate according to the invention in an amount effective to inhibit gastric acid secretion and a pharmaceutically acceptable carrier. The invention also provides methods of treatment for various acid-related gastrointestinal (GI) disorders.
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