4,5-dihydro-oxazol-2-yl amine derivatives
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United States of America Patent
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Aug 2, 2011
Grant Date -
Aug 20, 2009
app pub date -
Feb 12, 2009
filing date -
Feb 18, 2008
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Abstract
The present invention relates to a compounds of formula I, X, Ar, and m are as defined in the specification and claims and pharmaceutically active acid addition salts thereof. Compounds of the invention have Asp2 (β-secretase, BACE 1 or Memapsin-2) inhibitory activity and are useful for the treatment of diseases characterized by elevated β-amyloid levels or β-amyloid deposits, particularly Alzheimer's disease.
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