Circle probes and their use in the identification of biomolecules

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United States of America Patent

PATENT NO 7989166
APP PUB NO 20100047773A1
SERIAL NO

11911527

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Abstract

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The present invention provides oligonucleotides and methods for efficient detection of target nucleic acids using rolling circle replication. In one aspect, the oligonucleotides of the invention are characteristic in that they can be circularised without an external ligation template. In another aspect, the oligonucleotides of the invention are characteristic in that they can generate a free 3′end of the target nucleic acid necessary for rolling circle replication. The oligonucleotides and detection methods of the invention are useful e.g. as research tool and for diagnosis.

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Patent Owner(s)

Patent OwnerAddress
IN SITU RCP A/SNIELS JERNES VEJ 10 C/O NOVI A/S AALBORG OST 9220

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Koch, Jorn Erland Ry, DK 2 57
Lohmann, Jakob Schwalbe Ry, DK 4 108
Stougaard, Magnus Aarhus C, DK 10 109

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