Antimicrobial cathelicidin peptides
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United States of America Patent
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Jul 26, 2011
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N/A
app pub date -
Dec 29, 2006
filing date -
Dec 29, 2005
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Abstract
The invention relates to antimicrobial cathelicidin polypeptides related to a 38 amino acid peptide having SEQ ID NO:4. The invention provides for polypeptides having broad spectrum antimicrobial activity, nucleic acids and expression vectors encoding such polypeptides, as well as host cells and methods of reducing survival of a microbe. In addition, the invention also provides compositions, as well as articles of manufacture, that comprise a broad spectrum antimicrobial polypeptide.
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