Method for distributing a pharmaceutically active compound in an excipient
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United States of America Patent
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Jul 12, 2011
Grant Date -
Jan 24, 2008
app pub date -
Jul 24, 2006
filing date -
Jul 24, 2006
priority date (Note) -
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Abstract
A process for uniformly distributing a pharmaceutically active particulate material in a pharmaceutically inert particulate material includes steps of providing a first layer of a pharmaceutically inert particulate material, disposing a layer of a pharmaceutically active particulate material on the first layer of pharmaceutically inert particulate material, passing the layers of particulate material through a static mixer, and discharging the blended mixture from the static mixer. The process is particularly useful for blending a low dose, high potency drug having a propensity to stick to process equipment surfaces with pharmaceutically inert particulate materials, such as diluents and/or excipients.
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