Methods of treating, reducing, or preventing autoimmune conditions
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United States of America Patent
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Jul 5, 2011
Grant Date -
Jan 24, 2008
app pub date -
Jan 24, 2005
filing date -
Jan 23, 2004
priority date (Note) -
Expired
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Abstract
The present invention relates to methods and kits for treating, reducing, or preventing autoimmune conditions such as rheumatoid arthritis by administering to a mammal in need thereof an agent that modulates the expression level or biological activity of Toll-like receptor-9 (TLR-9). Also disclosed are screening methods that make use of TLR-9 for the identification of novel therapeutics for autoimmune conditions.
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