Thiolactones
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United States of America Patent
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Jun 28, 2011
Grant Date -
Feb 25, 2010
app pub date -
May 26, 2009
filing date -
Mar 3, 2003
priority date (Note) -
Expired
status (Latency Note)
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Abstract
This invention provides new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, inhibiting angiogenesis, effecting a TGF-β activity or a neuronal activity, and treating a glutamate abnormality, a compulsive disorder, neuropathy, pain, a prostate disease, cancer, Huntington's disease, diabetes, a retinal disorder or glaucoma.
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