Method of identifying a potential substrates of an O-methyltransferase

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United States of America Patent

PATENT NO 7966133
APP PUB NO 20090192720A1
SERIAL NO

12135950

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides crystalline O-methyltransferases and isolated non-native O-methyltransferases as well as sets of their structural coordinates. Also provided are methods of predicting the activity or substrate specificity of putative O-methyl-transferases, methods of identifying potential substrates of O-methyltransferases, and methods of identifying potential inhibitors of methyltransferases.

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Patent Owner(s)

Patent OwnerAddress
THE SALK INSTITUTE FOR BIOLOGICAL STUDIESLA JOLLA CALIFORNIA 92037

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dixon, Richard Ardmore, US 25 170
Noel, Joseph P San Diego, US 44 272
Zubieta, Chloe Grenoble, FR 8 3

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