Assays based on detection of photobleaching reaction products from dye catalytic complex
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United States of America Patent
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Jun 21, 2011
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Aug 19, 2010
app pub date -
Feb 17, 2009
filing date -
Feb 17, 2009
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Abstract
The present invention relates to the methods for assaying an analyte comprising a nucleic acid analog binding substrate in a sample, comprising reacting a catalytic complex comprising a nucleic acid analog, a nucleic acid analog specific binding substrate and a light reactive dye with a light stimulus, and detecting the presence or absence or amount of a reaction product of the catalytic complex and light stimulus. The present invention also relates to a method of assaying a nucleic acid analyte in a sample using an analyte-specific reporter complex. The present invention also relates to a method of assaying an analyte in a sample using a reporter molecule.
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