Time-domain method and apparatus for determining the depth and concentration of a fluorophore in a turbid medium

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United States of America Patent

PATENT NO 7960707
APP PUB NO 20070158585A1
SERIAL NO

10577527

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Abstract

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Methods and apparatuses for determining the depth and concentration of fluorophores in a turbid medium are disclosed. The method advantageously provides for a rapid estimation of the depth of the fluorophore using characteristics of a temporal point spread function. The concentration of the fluorophore can be determined using the method of the present invention by combining a calculated depth of the fluorophore with a measurement of the intensity of the emitted fluorescence. The intensity can be accurately measured by the apparatus disclosed herein which combine back-reflection and trans-illumination geometries for the source of light injecting and detection.

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Patent Owner(s)

Patent OwnerAddress
SOFTSCAN HEALTHCARE GROUP LTDROAD TOWN TORTOLA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gallant, Pascal Laval, CA 17 509
Hall, David Jonathan San Diego, US 8 110
Lesage, Frederic Montréal, CA 9 332
Ma, Guobin Dorval, CA 18 103

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