Quinazoline derivative
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United States of America Patent
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Jun 14, 2011
Grant Date -
Nov 6, 2008
app pub date -
May 30, 2005
filing date -
May 31, 2004
priority date (Note) -
Expired
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Abstract
This invention provides a compound or its pharmaceutically-acceptable salt of formula (I)represents the substituent of the formula (II) et al;represents NH, O or S; Y represents N or C; Ar is a divalent substituent derived from aryl et al, by removing two hydrogen atoms therefrom; the ring A represents a 5- or 6-membered heteroaryl group; this compounds has a histamine-H3 receptor antagonistic effect or a histamine-H3 receptor inverse-agonistic effect and is useful for preventive or remedy of metabolic system diseases, circulatory system diseases or nervous system diseases.
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