Promoter mutations that increase amyloid precursor protein expression

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7960117
APP PUB NO 20090217395A1
SERIAL NO

12225270

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to mutations in the amyloid precursor protein (APP) promoter region, whereby the mutations cause a significant increase in APP expression. The increase in APP expression is related to Alzheimer's disease, and the mutations can be used in Alzheimer's disease diagnosis, or in the construction of transgenic animal models for studying Alzheimer's disease.

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Patent Owner(s)

Patent OwnerAddress
VIB VZWRIJVISSCHESTRAAT 120 GENT B-9052
UNIVERSITEIT ANTWERPENPRINSSTRAAT 13 ANTWERPEN 2000

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Theuns, Jessie Antwerp, BE 1 0
van, Broeckhoven Christine Edegem, BE 6 52

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