/TEM-1 β-lactamase
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United States of America Patent
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Jun 7, 2011
Grant Date -
Oct 20, 2005
app pub date -
Dec 3, 2004
filing date -
Feb 2, 1998
priority date (Note) -
Expired
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Abstract
The present invention describes an assay method comprising: (A) generating (1) at least a first fragment of a reporter molecule linked to a first interacting domain and at least a second fragment of a reporter molecule linked to a second interacting domain, or (2) nucleic acid molecules that code for (A)(1) and subsequently allowing said nucleic acid molecules to produce their coded products; then, (B) allowing interaction of said domains; and (C) detecting reconstituted reporter molecule activity, where said reporter molecule can react with a penicillin- or a cephalosporin-class substrate.
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