Use of transthyretin as a biomarker for colorectal adenoma and/or carcinoma; method for detection and test system
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United States of America Patent
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May 31, 2011
Grant Date -
Aug 9, 2007
app pub date -
Aug 13, 2004
filing date -
Aug 13, 2004
priority date (Note) -
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Abstract
The invention is directed to a method for detecting colorectal adenoma and/or colorectal carcinoma comprising the steps: a) providing an isolated sample material which has been taken from an individual, b) determining the level of transthyretin in said isolated sample material, and c) comparing the determined level of transthyretin with a reference value. The invention is further directed to a method for discriminating between colorectal adenoma and colorectal carcinoma as well as to a method for monitoring the course of colorectal adenoma and/or colorectal carcinoma and/or the treatment of colorectal adenoma and/or colorectal carcinoma. Moreover, the invention is directed to a test system and an array for use in these methods. Furthermore, the invention is directed to the use of transthyretin as a biomarker for a detection of colorectal adenoma and/or colorectal carcinoma in an individual.
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