Pharmaceutical preparation and method of treatment of human malignancies with arginine deprivation

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United States of America Patent

PATENT NO 7951366
APP PUB NO 20050244398A1
SERIAL NO

10518223

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Abstract

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The present invention provides an isolated and substantially purified recombinant human arginase having sufficiently high enzymatic activity and stability to maintain Adequate Arginine Depletion in a patient. The present invention also provides a pharmaceutical composition comprising the modified invention enzyme and method for treatment of diseases using the pharmaceutical composition.

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Patent Owner(s)

Patent OwnerAddress
BIO-CANCER TREATMENT INTERNATIONAL LIMITEDROOM 511-513 5/F BIO-INFORMATICS CENTRE 2 SCIENCE PARK WEST HONG KONG SCIENCE PARK SHATIN NEW TERRITORIES

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cheng, Ning Man Hong Kong, CN 11 26
Leung, Yun Chung Hong Kong, CN 19 33
Lo, Wai Hung Hong Kong, CN 7 15

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