Process for the preparation of 3,4-disubstituted-thiazolidin-2-ones
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United States of America Patent
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May 24, 2011
Grant Date -
Nov 20, 2008
app pub date -
Jul 30, 2008
filing date -
Mar 23, 2006
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Expired
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Abstract
The present invention is directed to practical high-yielding synthetic processes for preparing 3,4-disubstituted-thiazolidin-2-ones, which do not compromise the absolute stereochemical integrity of the compounds. The present invention is also directed to novel compounds of 3,4-disubstituted-thiazolidin-2-ones. The compounds prepared by the present invention are useful in the synthesis and manufacture of compounds (such as latrunculins and/or their analogs) for treating diseases or conditions associated with inhibiting actin polymerization.
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