Telomelysin/GFP-expressing recombinant virus
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United States of America Patent
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May 17, 2011
Grant Date -
Mar 30, 2006
app pub date -
Jun 21, 2005
filing date -
Sep 29, 2004
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Abstract
The present invention provides a reagent for cancer cell detection or cancer diagnosis. The present invention relates to a reagent for cancer cell detection, comprising a recombinant virus where a replication cassette comprising a promoter from human telomerase, an E1A gene, an IRES sequence and an E1B gene in this order is integrated in E1 region of the viral genome and a labeling cassette comprising a gene encoding a labeling protein and a promoter capable of regulating the expression of the gene encoding the labeling protein is integrated in E3 region of the viral genome.
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