Attenuated mycobacteria as vectors for gene delivery to mammalian cells
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United States of America Patent
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May 10, 2011
Grant Date -
Oct 30, 2008
app pub date -
Jan 12, 2006
filing date -
Jan 12, 2005
priority date (Note) -
Expired
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Abstract
Provided are mycobacteria comprising a recombinant gene operably liked to a mammalian promoter that directs expression of the recombinant gene from a mammalian cell. Also provided are mammalian cells comprising the above mycobacteria. Additionally provided are mycobacterial plasmids capable of replication in a mycobacterium. Further provided are methods of expressing a recombinant gene in a mammalian cell.
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