Methods for determining sensitivity to microtubule-stabilizing agents comprising ixabepilone by measuring the level of estrogen receptor 1
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United States of America Patent
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Apr 26, 2011
Grant Date -
Dec 25, 2008
app pub date -
Oct 1, 2007
filing date -
Nov 30, 2004
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Abstract
Biomarkers that are useful for identifying a mammal that will respond therapeutically or is responding therapeutically to a method of treating cancer that comprises administering a microtubule-stabilizing agent. In one aspect, the cancer is breast cancer, and the microtubule-stabilizing agent is an epothilone or analog or derivative thereof, or ixabepilone.
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