Substituted 2-indolinone as PTK inhibitors containing a zinc binding moiety

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United States of America Patent

PATENT NO 7928136
APP PUB NO 20080125478A1
SERIAL NO

11852419

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Abstract

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The present invention relates to substituted 2-indolinone containing zinc-binding moiety based derivatives that have enhanced or unique properties as inhibitors of protein tyrosine kinase (PTK) receptors and their use in the treatment of PTK related diseases and disorders such as cancer. The said derivatives may further act as HDAC inhibitors.

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Patent OwnerAddress
CURIS INCFOUR MAGUIRE ROAD LEXINGTON MA 02421

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cai, Xiong Belmont, US 100 1263
Gould, Stephen San Carlos, US 51 1404
Qian, Changgeng Wayland, US 73 747

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  • 1 Citation Count
  • A61K Class
  • 10.68 % this patent is cited more than
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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges7424023113748323813073422412123001 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +025050075010001250150017502000225025002750300032503500375040004250

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