Substituted 2-indolinone as PTK inhibitors containing a zinc binding moiety
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United States of America Patent
Stats
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Apr 19, 2011
Grant Date -
May 29, 2008
app pub date -
Sep 10, 2007
filing date -
Sep 11, 2006
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention relates to substituted 2-indolinone containing zinc-binding moiety based derivatives that have enhanced or unique properties as inhibitors of protein tyrosine kinase (PTK) receptors and their use in the treatment of PTK related diseases and disorders such as cancer. The said derivatives may further act as HDAC inhibitors.
First Claim
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Family

- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
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CURIS INC | FOUR MAGUIRE ROAD LEXINGTON MA 02421 |
International Classification(s)
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
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Cai, Xiong | Belmont, US | 100 | 1263 |
# of filed Patents : 100 Total Citations : 1263 | |||
Gould, Stephen | San Carlos, US | 51 | 1404 |
# of filed Patents : 51 Total Citations : 1404 | |||
Qian, Changgeng | Wayland, US | 73 | 747 |
# of filed Patents : 73 Total Citations : 747 |
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Patent Citation Ranking
- 1 Citation Count
- A61K Class
- 10.68 % this patent is cited more than
- 14 Age
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Maintenance Fees
Fee | Large entity fee | small entity fee | micro entity fee | due date |
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Fee | Large entity fee | small entity fee | micro entity fee |
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Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
Full Text

Legal Events
Date | Code | Event | Description |
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May 18, 2015 | STCH | INFORMATION ON STATUS: PATENT DISCONTINUATION | free format text: PATENT EXPIRED DUE TO NONPAYMENT OF MAINTENANCE FEES UNDER 37 CFR 1.362 |
Apr 19, 2015 | FP | LAPSED DUE TO FAILURE TO PAY MAINTENANCE FEE | Effective Date: Apr 19, 2015 |
Apr 19, 2015 | LAPS | LAPSE FOR FAILURE TO PAY MAINTENANCE FEES | |
Nov 28, 2014 | REMI | MAINTENANCE FEE REMINDER MAILED | |
Apr 19, 2011 | I | Issuance | |
May 29, 2008 | P | Published | |
Feb 11, 2008 | AS | ASSIGNMENT | free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:CAI, XIONG;QIAN, CHANGGENG;GOULD, STEPHEN;REEL/FRAME:020491/0270;SIGNING DATES FROM 20080109 TO 20080130 Owner name: CURIS, INC., MASSACHUSETTS free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:CAI, XIONG;QIAN, CHANGGENG;GOULD, STEPHEN;SIGNING DATES FROM 20080109 TO 20080130;REEL/FRAME:020491/0270 Owner name: CURIS, INC., MASSACHUSETTS |
Sep 10, 2007 | F | Filing | |
Sep 11, 2006 | PD | Priority Date |

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