5-anilinoimidazo[1,5-a]-pyridines inhibitors of MEK kinase
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United States of America Patent
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Apr 12, 2011
Grant Date -
Jan 7, 2010
app pub date -
Apr 29, 2009
filing date -
Dec 19, 2007
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Abstract
The invention relates to imidazopyridines of formula I with anti-cancer and/or anti-inflammatory activity and more specifically to imidazopyridines which inhibit MEK kinase activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth or treating a hyperproliferative disorder, or treating an inflammatory disease in a mammal. The invention also relates to methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.
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