Processes for the preparation of hydroxylamines
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United States of America Patent
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Apr 5, 2011
Grant Date -
Oct 2, 2008
app pub date -
Jun 9, 2008
filing date -
May 2, 2005
priority date (Note) -
Expired
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Abstract
The present invention relates generally to novel methods for the synthesis of O-(6-pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine which is an essential reagent in the synthesis of one of the bridged erythromycin derivatives and their respective pharmaceutically acceptable salts in PCT Application WO 03/097659 A1. In particular, the present invention relates to processes and intermediates for the preparation of a compound of formula (Ia):
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