Organic compound and method for producing radioactive halogen-labeled organic compound using the same
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United States of America Patent
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Mar 22, 2011
Grant Date -
Apr 23, 2009
app pub date -
May 15, 2006
filing date -
May 23, 2005
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Abstract
It is intended to provide a labeling precursor compound used for selectively producing radioactive halogen-substituted syn-1-amino-3-cyclobutane-carboxylic acids, and to provide a process for producing a radioactive halogen-substituted syn-1-amino-3-cyclobutane-carboxylic acid using the labeling precursor compound. A labeling precursor is used in which a phthalimide group is used as a protective group for protecting the amino group. The syn-form of the radioactive halogen-substituted 1-amino-3-cyclobutane-carboxylic acid can be selectively produced by labeling the labeling precursor with a radioactive halogen followed by deprotecting.
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