Truncated DANCE, DANCE complex and method of using these
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United States of America Patent
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Mar 15, 2011
Grant Date -
Sep 20, 2007
app pub date -
Mar 4, 2005
filing date -
Mar 29, 2004
priority date (Note) -
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Abstract
A method of screening for a medicine capable of regulating generation of elastic fibrous tissue; and various means that are requisite for the method. In particular, the invention includes a polypeptide obtained by cleaving DANCE and a polynucleotide coding for the polypeptide; a method of cleaving DANCE; an antibody against the polypeptide obtained by cleaving DANCE; a method of measuring the amount of DANCE cleavage and a kit therefore; a DANCE variant and its polynucleotide; various DANCE complexes and a method of preparing such; a method of screening for a substance capable of regulating DANCE or a DANCE-specific protease, and a substance obtained by such screening method; an agent for regulating generation of elastic fibrous tissue; and a kit with DANCE and a polynucleotide coding for the same.
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