Protein kinase inhibitors and methods for identifying same
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United States of America Patent
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Mar 8, 2011
Grant Date -
Nov 1, 2007
app pub date -
Feb 14, 2005
filing date -
Feb 13, 2004
priority date (Note) -
Expired
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Abstract
Inhibitors of protein kinase C (PKC)α, PKCδ and PKCζ are provided which are selective for those PKC isotypes. Combinatorial libraries for identifying protein kinases are also provided, as are methods of identifying protein kinases using those libraries. Additionally, methods of treating a mammal having a deleterious condition, where the condition is dependent on a protein kinase for induction or severity, are provided. Methods of inhibiting protein kinases are also provided.
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