Method of detecting or monitoring a malignant plasma cell disease
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Mar 1, 2011
Grant Date -
Jul 10, 2008
app pub date -
Jan 26, 2006
filing date -
Jan 27, 2005
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
A method of detecting or monitoring a malignant plasma cell disease comprising detecting in a sample the ratio between the relative amounts of immunoglobulins having: (i) a heavy chain class bound to λ light chains; and (ii) immunoglobulins having the same heavy chain class but bound to κ light chains. Preferably the ratio is determined by (1) a method wherein the ratio is determined using: (i) an antibody, or a fragment thereof, having specificity for a heavy chain class at the same time as having specificity for a first light chain in combination with either: (ii) an antibody, or a fragment thereof, having specificity for the heavy chain class at the same time as having specificity for the second light chain; or (iii) an antibody, or fragment thereof, having specificity for the heavy chain and a further antibody, or fragment thereof, having specificity for the second light chain. (2) a method wherein the ratio is determined using: (i) at least one antibody, or a fragment thereof, specific for the heavy chain class; (ii) an antibody, or a fragment thereof, specific for λ light chains; and (iii) an antibody, or a fragment thereof, specific for κ light chains; or Antibodies specific for a heavy chain class at the same time as having specificity for a specific light chain are also provided.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully