Methods for characterizing enzyme inhibitors

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United States of America Patent

PATENT NO 7897330
APP PUB NO 20090148858A1
SERIAL NO

11719528

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Abstract

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Methods for characterizing a biochemical reaction and analysis of reaction products by establishing continuously variable concentration gradients of one or more reagents of the biochemical reaction are provided. Methods for determining mechanism of inhibition or activation, potency of inhibition or activation, or both of an enzyme inhibitor or activator, respectively, are also provided. The continuously variable concentration gradients can be established in a microfluidic chip.

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AB SCIEX LLC500 OLD CONNECTICUT PATH FRAMINGHAM MA 01701

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Patel, Mehul Ambler, US 218 7464
Schmidt, Dawn M Durham, US 2 35
Tew, David G Harlow Essex, GB 7 84
Thrall, Sara H Collegeville, US 4 21

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