Substrates and assays for β-secretase

United States of America Patent

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Feb 15, 2011
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Dec 16, 2004
app pub date
Mar 16, 2004
filing date
Jul 19, 2000

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Abstract

The present invention is directed to novel substrates for Hu-Asp. More particularly, the invention provides peptide substrates and fusion polypeptide substrates comprising a β-secretase cleavage site. Methods and compositions for making and using the peptides are disclosed.

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Patent Owner	Address
ELAN PHARMACEUTICALS INC	800 GATEWAY BOULEVARD SOUTH SAN FRANCISCO CA 94080

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C40B:COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL ....

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Inventor Name	Address	# of filed Patents	Total Citations
Bienkowski, Michael Jerome	Ballwin, US	17	73
Emmons, Thomas L	Wentzville, US	11	34
Gurney, Mark E	Grand Rapids, US	88	598
Heinrikson, Robert L	Plainwell, US	36	325
Tomasselli, Alfredo G	Wildwood, US	12	42
Yan, Riqiang	Pepper Pike, US	37	344

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Substrates and assays for β-secretase

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United States of America Patent

10801509

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PATENT NO	7888291
APP PUB NO	20040254341A1
SERIAL NO	10801509
DOCKET NO

US Family Size	Non-US Coverage
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DATE PUBLISHED	PUBLICATION/PATENT NO.	PUBLICATION TYPE
February 15, 2011	US,7888291,B2 US7888291B2	GRANTED PATENT AS SECOND PUBLICATION
December 16, 2004	US,20040254341,A1 US20040254341A1	FIRST PUBLISHED PATENT APPLICATION

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10801509

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