Method of stabilising or reactivating a creatinine sensor with a divalent manganese ion
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United States of America Patent
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Feb 15, 2011
Grant Date -
Dec 7, 2006
app pub date -
May 16, 2006
filing date -
May 17, 2005
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Abstract
A method is provided for stabilizing a creatinine sensor comprising creatininase as a bioactive molecule. The creatininase is stabilised by exposing it to a sufficient amount of a divalent manganese ion. This result may be obtained by exposing the sensor to a solution comprising the divalent manganese ion or by introducing a composition within the sensor providing sustained release of the divalent manganese ion.
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