Methods for treating viral infections using polyamine analogs
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United States of America Patent
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Feb 1, 2011
Grant Date -
Apr 5, 2007
app pub date -
Sep 25, 2006
filing date -
Sep 23, 2005
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Abstract
Methods for treating viral infections using polyamine analogs, including mitoguazone (MGBG), are provided. In these methods, polyamine analogs destroy macrophages that act as viral reservoirs, facilitating the destruction of the viruses that dwell within the macrophages. Examples of viral infections that may be treated with the present methods include, but are not limited to, infections from human immunodeficiency viruses. These methods differ from previous methods of treatment using polyamine analogs, wherein the polyamine analogs were administered only as anti-tumor agents.
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