Carbostyril derivatives for accelerating salivation
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United States of America Patent
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Feb 1, 2011
Grant Date -
May 17, 2007
app pub date -
Jul 7, 2004
filing date -
Jul 30, 2003
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Abstract
Novel pharmaceutical composition for accelerating salivation and for prophylaxis and/or treatment of xerostomia, which comprises as an active ingredient a carbostyril compound of the formula (1), wherein R is a halogen atom, and the substitution position of the subsistuent on said carbostyril nucleus is the 3- or 4-position, and the bond between the 3- or 4-positions of the carbostyril nucleus is either a single bond or a double bond, or a pharmaceutically acceptable salt thereof. The pharmaceutical composition of the present invention exhibits an accelerating activity of salivation, and is useful in the prophylaxis or treatment of Xerostomia or hyposalivation.
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