Method of treating mouse carrying human hepatocytes
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United States of America Patent
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Jan 18, 2011
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app pub date -
Jun 30, 2006
filing date -
Jun 30, 2005
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Abstract
Human adult hepatocytes are transplanted into an immunodeficient hepatopathy mouse and then human growth hormone is administered to the mouse to thereby elevate twice or more the replacement ratio by the human adult hepatocytes having been transplanted. Further, human growth hormone is administered to an immunodeficient hepatopathy mouse carrying human young hepatocytes transplanted thereinto so as to improve fatty liver of the mouse in which about 70% or more of the hepatocytes have been replaced by the human hepatocytes.
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