GEF-H1b: biomarkers, complexes, assays and therapeutic uses thereof

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United States of America Patent

PATENT NO 7871786
APP PUB NO 20090130695A1
SERIAL NO

12232134

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Abstract

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The present invention relates to diagnosing abnormal cell proliferation in biological samples and screening for drugs which inhibit, reduce or abolish cell growth, especially tumorigenic cell growth, by detecting a phosphovariant isoform of a guanine nucleotide exchange factor biomarker, such as the novel GEF-H1S.

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Patent Owner(s)

Patent OwnerAddress
SUGEN INCSOUTH SAN FRANCISCO CA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Callow, Marinella G San Mateo, US 6 1
Gishizky, Mikhail L Menlo Park, US 6 0
Jallal, Bahija Menlo Park, US 33 267
Smeal, Tod R San Francisco, US 6 1
Zozulya, Sergey Los Angeles, US 100 4120

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