HCV multiple epitope fusion antigens with modified proteolytic cleavage sites and uses thereof

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United States of America Patent

PATENT NO 7871625
SERIAL NO

11661577

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Abstract

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Modified HCV multiple epitope fusion antigens (MEFAs) are described. The proteins include modified sequences such that proteolytic cleavage of the MEFAs by HCV NS3 protease is inhibited. HCV immunoassays including the modified MEFAs are also described.

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Patent Owner(s)

Patent OwnerAddress
GRIFOLS WORLDWIDE OPERATIONS LIMITEDGRANGE CASTLE BUSINESS PARK GRANGE CASTLE CLONDALKIN DUBLIN 22 IRELAND

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chien, David Alamo, US 15 176
Coit, Doris Petaluma, US 25 362
George-Nascimento, Carlos Walnut Creek, US 11 34
Lin, Sansan Albany, US 4 138
Medina-Selby, Angelica San Francisco, US 35 387
Tandeske, Laura San Leandro, US 6 23

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