Fusion protein of exendin-4 to a transferrin (Tf) polypeptide
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United States of America Patent
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Jan 11, 2011
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Sep 24, 2009
app pub date -
Jul 24, 2007
filing date -
Jul 24, 2006
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Abstract
The invention provides fusion proteins comprising an exendin-4 fused to a transferrin (Tf) via a polypeptide linker, as well as corresponding nucleic acid molecules, vectors, host cells, and pharmaceutical compositions. The invention also provides the use of the exendin-4/Tf fusion proteins for treatment of Type II diabetes, obesity, and to reduce body weight.
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