Antifungal agents

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United States of America Patent

PATENT NO 7863465
SERIAL NO

11727927

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to novel enfumafungin derivatives of formula I and pharmaceutically acceptable salts thereof, their synthesis, and their use as inhibitors of (1,3)-β-D-glucan synthase. The present compounds and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions comprising the present compounds and pharmaceutically acceptable salts thereof, are useful for treating or preventing antifungal infections and associated diseases and conditions.

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Patent Owner(s)

Patent OwnerAddress
SCYNEXIS INC3501 C TRICENTER BOULEVARD DURHAM NC 27713

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Balkovec, James M Martinsville, US 55 334
Bouffard, Frances Aileen Scotch Plains, US 6 69
Dropinski, James Colts Neck, US 1 6
Fan, Weiming Chapel Hill, US 15 52
Greenlee, Mark L Plainfield, US 42 307
Li, Keqaing Cary, US 1 6
Liu, Hao Raleigh, US 555 2317
Mamai, Ahmed Raleigh, US 21 54
Meng, Dongfang Westfield, US 31 198
Peel, Michael Chapel Hill, US 15 218
Tse, Bruno San Diego, US 18 98

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