Wortmannin analogs and methods of using same in combination with chemotherapeutic agents
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United States of America Patent
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Dec 28, 2010
Grant Date -
Apr 2, 2009
app pub date -
Sep 23, 2008
filing date -
Jul 9, 2004
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Abstract
Novel wortmannin analogs and their use in inhibiting PI-3-kinase activity in mammals and the treatment or prevention of cancer and tumor formation in a subject are described herein. Preferably, the wortmannin analogs may be administered with other chemotherapeutic agents in the treatment of cancer.
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