Method of treating human volume expansion mediated hypertension employing resibufogenin

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United States of America Patent

PATENT NO 7858604
APP PUB NO 20070014722A1
SERIAL NO

11484162

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method of treating volume expansion mediated hypertension including administering a therapeutically effective dose of resibufogenin to a patient having volume expansion mediated hypertension. A method for the determination of the presence of volume expansion mediated hypertension may be by determining whether there has been a substantial elevation in marinobufagenin which may be blood-derived or urine-derived and if such elevation does exist, concluding that volume expansion mediated hypertension does exist. The method may advantageously be practiced by employing urine, blood serum or blood plasma as the body specimen in determining whether a patient has volume expansion mediated hypertension. In another embodiment, bufodienolide derivatives other than resibufogenin may be employed in lieu of thereof or in combination therewith. In another embodiment, resibufogenin analogues may be employed in the treatment of volume expansion mediated hypertension.

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Patent Owner(s)

Patent OwnerAddress
PUSCHETT JULES BTHE SPIRES 2001 HOLCOMBE BOULEVARD #806 HOUSTON TX 77030

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Puschett, Jules B New Orleans, US 22 14

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